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In summary, although current research on PDEVs is still in its early exploratory stages, existing preliminary findings already underscore their promising therapeutic potential in tissue engineering

Moreover, ferroptosis-associated damage molecules such as high mobility group box-1 (HMGB1) and chemokine CXCL2 can directly impair the functional stability of brain microvascular endothelial cells

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The nucleic acid associated with a lipid may be encapsulated in the aqueous interior of a liposome, interspersed within the lipid bilayer of a liposome, attached to a liposome via a linking molecule that is associated with both the liposome and the oligonucleotide, entrapped in a liposome, complexed with a liposome, dispersed in a solution containing a lipid, mixed with a lipid, combined with a lipid, contained as a suspension in a lipid, contained or complexed with a micelle, or otherwise associated with a lipid

(Cambridge (MA): MIT Press)

These two isoforms exhibit also similar tendency in Pilo-induced acute epileptic seizure while HDAC3 and HDAC8 are significantly reduced at the mRNA level in the chronic epilepsy [37]