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In truth, the company made the switch to appeal to women, as much as men

Some very explicit, almost gruesome pictures may be necessary, FDA Commissioner Margaret Hamburg said in an interview with The Associated Press

We urge President Biden and his administration to seize this historic opportunity to improve our nations health, promote health equity and save lives from cancer and other tobacco-related diseases

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As smoking tends to aggregate between spouses (smokers are more likely to marry smokers), misclassification of active smoking would tend to be differential on the basis of spousal smoking (the exposure under investigation)

60 of these cause cancer and include insecticide, car battery fluid, arsenic poison & hydrogen cyanide