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34 Respiratory diseases In chronic obstructive pulmonary disease (COPD), aging-associated immune dysfunction exacerbates lung damage through multiple pathways: epithelial barrier integrity deterioration, impaired mucus clearance, and alveolar macrophages with low phagocytic capacity

Mezziani, M.-F

Before you can effectively manage histamine, you need to reduce inappropriate mast cell activation

Current treatment options are limited and often only slow disease progression

Adam EK, Quinn ME, Tavernier R, McQuillan MT, Dahlke KA, Gilbert KE

We developed a PAM-specific amidation assay that utilizes the naturally occurring substrate Adrenomedullin-Gly (ADM-Gly, 153)