J Hepatol 36:7277 Shao T, Verma HK, Pande B, Costanzo V, Ye W, Cai Y, Bhaskar L (2021) Physical activity and nutritional influence on immune function: an important strategy to improve immunity and health status

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Micromachines 9 , 430 (2018)
At concentrations of 1 pM1 nM, DSIP stimulated calcium-dependent release of immunoreactive Met-enkephalin from rat lower brainstem slices in vitro suggesting any antinociceptive effects observed in animal models may be mediated through endogenous opioid peptide release rather than direct receptor binding [7]