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302 The ER is the major organelle for lipid synthesis in hepatocytes, and a high concentration of intracellular lipids can activate ER stress by disrupting Ca 2+ homeostasis

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aryl refers to an aromatic group having at least one carbocyclic aromatic group or heterocyclic aromatic group, which may be unsubstituted or substituted by one or more groups selected from halogen, haloalkyl, hydroxy, alkoxy, carbonyl, alkylamido, nitro, amino, dialkylamino, carboxy, thio or thioalkyl

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