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Notably, the presence of A exacerbates mitochondrial ROS production and impairs mitophagy, further enhancing mitochondrial dysfunction [65, 66]

J Biol Chem 279:2345323462 Buettner GR (1993) The pecking order of free radicals and antioxidants: lipid peroxidation, a-tocopherol, and ascorbate

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This acid is required by the body to liberate vitamin B12 from food, so without it, the nutrient cant be absorbed naturally

EZ contributed to the organic acids determination

demonstrated that rabbit hemorrhagic disease virus (RHDV) infection induces NF-B activation, and Keap1 interaction reduces Nrf2-related antioxidant function 136