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The IL-6 described above may interfere with estrogen synthesis in GCs, impacting oocyte development (88)

*Correspondence: Alejandro Gonzlez-Candia [email protected] This article was submitted to Integrative Physiology, a section of the journal Frontiers in Physiology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Treated rats showed reduced activation of microglia and astrocytes in the substantia nigra and striatum, as evidenced by lower expression of glial markers compared to untreated 6-OHDA controls (56)

This is further demonstrated by immunostaining of Day 45 iHLOs, which shows a significant increase and clustering of DES-expressing cells forming a solid structure distinct from the cystic structure composed of KRT7- or CYP3A4-expressing epithelial cells (Supplementary Fig

[DOI] [PMC free article] [PubMed] [Google Scholar] [290].Ricotta EE, Lai YL, Babiker A, et al

Cancer Cell 31 , 3549 (2017)