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Research shows that at least 10% of people over 60 have B12 deficiency, and many younger adults are also affected due to dietary choices or absorption problems

When to Consider Testing Testing may be useful: Before starting a GLP-1 medicine After a meaningful treatment change When diabetes goals are not being met When persistent gastrointestinal symptoms develop When food or fluid intake has significantly decreased When kidney or liver risk is already present When a prior result was abnormal When a healthcare provider recommends follow-up Testing frequency should be based on individual risk rather than an automatic monthly or quarterly panel for everyone

(PubMed) Chrysant SG, Chrysant GS