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While this risk has not been confirmed in human epidemiological studies, patients with personal or family history of MTC or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) should not use orforglipron or any GLP-1 receptor agonist

Another plus: The capsule is pretty small in size with a soft outer shell, said Paige, explaining, This capsule is easy to swallow since it is so small. She rated it a 5 out of 5 for swallowability