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Taken together, these oxidant detoxification mechanisms will lead to a depletion of the GSH pool, if the oxidant exposure is greater than the ability of the cell to produce and recycle oxidized GSH

Policy implications Smokers who also drank 15+ units/week had the highest risk of dying from all the causes compared to the other groups

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Moreover, this study is not an individual patient meta-analysis, where effect pooling can be performed using a statistical model that incorporates a uniform set of covariates

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