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Another approach to target apoE receptors is the use of apoE peptides that include motifs corresponding to the apoE receptor binding region

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This reduces the editing of viral DNA by APOBEC3G, thereby enhancing the replicative capacity and immune evasion of HIV-1 ( Cyclic GMP-AMP synthase (cGAS) is a cytosolic DNA sensor that activates innate immunity and is crucial for cellular senescence ( 3.3 Small GTPases as substrate receptors for CUL5 Small GTPases, members of the Ras superfamily, regulate their activity through binding to GTP (guanosine triphosphate) or GDP (guanosine diphosphate), playing pivotal roles in intracellular signaling ( Small GTPases, members of the Ras superfamily, regulate their activity through binding to GTP (guanosine triphosphate) or GDP (guanosine diphosphate) and play essential roles in intracellular signal transduction