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Front Plant Sci 3:82 Dore CMPG, Alves MGCF, Will LSEP, Costa TG, Sabry DA, de Souza Rgo LAR, Accardo CM, Rocha HAO, Filgueira LGA, Leite EL (2013) A sulfated polysaccharide, fucans, isolated from brown algae Sargassum vulgare with anticoagulant, antithrombotic, antioxidant and anti-inflammatory effects

B The inhibition of proliferation by Rapa from 0 to 8 nM, and the IC 50 for the cytotoxic effect of BPH-1 and WPMY-1 cells was 2.67 and 3.24 nM, respectively

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For example, wild-type TP53 is able to inhibit glycolysis by suppressing the expression of GLUT1, GLUT3, and GLUT4 (160, 161), and regulating the expression of enzymes involved in the glycolytic pathway, such as HK2 (162), phosphofructokinase 1 (PFK1) (163), phosphoglycerate mutase (PGM) (163), pyruvate dehydrogenase (PDH), parkin 2 (PARK2) (164), and pyruvate dehydrogenase kinase (PDK2) (165)

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