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104,105,106,107 For example, of the 4 (subtypes of) CRPC models, BCL-xL is upregulated in VCaP-AI (Fig

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The AR cyto BCL2 + (LAPC4-AI) subtype of CRPC is susceptible to BCL-2 inhibition Hereafter, we extended our study to address whether BCL-2 plays a functional role in CRPC progression and may represent a therapeutic vulnerability in diverse subtypes of CRPC (Figs