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The outcome measures were the Visual Analog Scale (VAS), Japanese Orthopaedic Association (JOA) score, Oswestry Disability Index (ODI), serum inflammatory factor expression, adverse surgical events, duration of postoperative hospitalization, and modified MacNab criteria

Unknown long-term profile: While short- and mid-term studies show good tolerability, the long-term safety of chronic Cagrilintide use is still being evaluated in Phase III trials

Moreover, consistent with the observations in zebrafish, TUNEL assays revealed that the apoptosis of GAD67-positive cells increased significantly in mice (Fig

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