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Recent findings highlight a dysregulation characterized by a T-helper 1 (Th1)/T-helper 2 (Th2) imbalance, which promotes abnormal immune responses, ultimately contributing to the disease pathology [54]

Shotgun metagenomics offers functional resolution but remains costly and analytically complex, with few large-scale studies in constipation-depression comorbidity

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The maintenance of intracellular GSH homeostasis involves both synthesis and degradation mechanism [14]

Markedly, these bioactive compounds have been specified to inhibit the proliferation of breast cancer cells in vitro [9]