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However, their therapeutic index is often narrowas exemplified by deferoxamine, which, despite being well-studied, is currently limited to treating acute iron poisoning and conditions involving chronic blood transfusions (e.g., thalassemia)

Ann Thorac Surg 106(1):235-241, 2018

In summary, low plasma selenium levels are associated with an increased risk of IBD

3.79 (dd, J= 9.3, 5.1 Hz, 1 H)

and (3) Dual-action therapeutics exemplified by Targ-TAP (scFvTarg-tick anticoagulant peptide fusion), demonstrating synergistic antiplatelet/anticoagulant activity that reduces infarct size and preserves cardiac function in vivo [151,152,153]