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Due to variations in hydroxylation pattern and chromophore ring (ring C), they can be further classified into different subgroups such as flavonoids, flavanones, isoflavonoids, flavanols, flavan-3-ols and anthocyanins

An ultra high performance liquid chromatography with tandem mass spectrometry method for simultaneous determination of thirteen components extracted from Radix Puerariae in rat plasma and tissues: application to pharmacokinetic and tissue distribution study

A., Mazurek, S

Zheng W, Ning K, Shi C, et al

HNSCC includes different subgroups, different primary sites (oral cavity, Larynx, Pharynx, etc.) and different driver gene backgrounds

More important, their results revealed that ACN can significantly decrease MDA levels which is a biomarker for lipid peroxidation secondary to generation of ROS and reduce inflammation by preventing upregulation of pro-inflammatory cytokines, such as Interleukin 6 (IL-6), Interleukin 1b (IL-1b) and chemokine (C-X-C motif) receptor 2 (Cxcr2) (Donepudi et al., 2011)