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Polymorphisms in the SIRT1 gene, such as SNPs (rs10997870, rs12778366), are associated with anxiety disorders, panic disorder, and social phobia [218]

B12 plays a vital role in supporting this infrastructure

This emphasizes the significant role of vitamin B12 in DNA synthesis, myelin sheath maintenance, and cell metabolism, underscoring its essential contribution to promoting good health

The length of CAG repeats is inversely correlated with the age of disease onset (Layburn et al., 2022), where longer repeats lead to earlier symptom manifestation (Farrer et al., 1992)