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This matrix acts as a nucleation scaffold, attracting and organizing calcium and phosphate ions from saliva into new hydroxyapatite crystals effectively rebuilding enamel from the inside out without drilling or restoration

Presence of three types of ligand-gated glutamate ion channel receptors such as N-methyl-D-aspartate, -amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid, and kainite receptors has been known for a long time

115 Mammalian xanthine oxidoreductase (XOR), one enzyme in purine catabolism, can exist in both dehydrogenase (XDH) form, which prefers NAD + as the electron acceptor, and XO form, which transfers the electrons directly to O 2 , leading to the formation of O 2 and H 2 O 2

Gut microbial-derived carboxylesterases and azoreductases promote the metabolism of angiotensin-converting enzyme inhibitors and sulfonamide drugs, respectively (Sun et al., 2019

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