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The theory described in the peptide literature is that a GHRH analog (signal one) and a ghrelin-receptor agonist (signal two) act in a complementary, even synergistic, way producing a larger GH pulse together than either pathway alone, because the pituitary carries co-receptors for both inputs

This makes it a practical option for studies where frequent administration is required

Acta Allergol 1967:22:299306

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Q: How often should glutathione injections be given

This is the second messenger system that leads to PKC activation and calcium mobilization