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At that point the remaining free radicals and toxins steal electrons from the cells organelles, membranes, and DNA, causing substantial damage and generating even more free radicals

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Figure 13 summarizes key intracellular glutathione (GSH) sensing strategies, encompassing fluorescent probes that detect reduced GSH through light emission, enzymatic biosensors that generate electrical signals via GSHNAD(P)H redox cycling, quantum nanoprobes that enable high-resolution fluorescence shifts, and nanomaterial-based sensors that act as GSH-responsive reporters for gene editing and signal amplification

doi: 10.3389/fnut.2025.1627949 Received 14 May 2025 Accepted 11 July 2025 Published 30 July 2025 Volume 12 - 2025 Edited by Hariprasath Lakshmanan, JSS Academy of Higher Education and Research, India Reviewed by Marisabel Mecca, Oncological Center of Basilicata (IRCCS), Italy Mohit Agrawal, K

Neuron 109 , 11001117.e10 (2021)

For example, drug inactivation is a strategy that bacteria adopt by producing enzymes that chemically modify or destroy antibiotics