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From this preliminary screening, we selected 43 compounds that showed at least 50% inhibition in all three assays for further doseresponse studies (Supplementary Tables 26)

Therefore, more negative potentials are assigned to reaction systems that have a greater tendency to donate electrons (i.e., systems that tend to oxidize most easily)

N Engl J Med 344:350-362

Metabolic flux This is the rate at which metabolites flow through a metabolic pathway in a biological system

Further, in fructose HFD-induced models, ovariectomy has been shown to reverse the reduced susceptibility of female mice to liver damage 92

Liver disease