The Refined Crystal Structure
This depletion is associated with increased oxidative stress and a higher risk of age-related diseases
Oligodendrocytes and Myelin Dysfunction : Degeneration of oligodendrocytes disrupts myelin sheath integrity, leading to impaired axonal action potential conduction and neural integrity
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The anti-inflammatory effects remained intact even in aged brains (albeit in mouse models)

Editorials Brunelli, A, Antonoff, MB, Petersen, RH, Stiles, BM, Wigle, DA, Platz, JJ, Muesse, JL, Louie, BE, Grenda, T, Daddi, N, Swisher, SG , Makey, I, Yendamuri, S, Khandhar, S, Schipper, PH, Linsky, PL, Liptay, MJ, Herrera, LJ, Pechet, TT, White, A, Wood, DE, Brandt, W, Martin, LW, Patterson, A, Seder, CW, Lanita, M, Molena, D, Lee, JM, Healy, DG, Decker, G, Sandri, A, Sihoe, AD, Zairi, S, Ruffini, E, Dunning, J, Raveglia, F, Maurizi, G, Kleontas, A, Sznt, Z, Depypere, L, Nosotti, M, Hudson, J, Caruana, EJ, Mitchell, JD, Gonfiotti, A, Pages, PB, Schneiter, D, Asadi, N, Aranda, J, Congregado, M, Bill, A, Backhus, LM, Bertani, A, Falcoz, PE, Nadal, SB, Rosso, L, Gatts, G, Augustin, F, Milton, R, Terra, R, Vannucci, F, Van Raemdonck, D, Waller, D, Gasparri, MG, Reddy, RM, Schreurs, WH, Saftic, I, Minervini, F, Tosi, D, Solli, P, Scarci, M, Gooseman, MR, Gossot, D, Alvarez, A, Vallieres, E, Toker, SA, Welcker, K, Aramini, B, Guerrera, F, Jimenez, M, Furak, J, Blkbas, S, Durand, M, Thomas, PA, Luzzi, L, Hugen, N, Aigner, C, Joseph, LL, Chiappetta, M, Prez, MR, Minasyan, A, Filose, PL, Elkhayat, H, Kim, YT, Pompili, C, Shargall, Y, Wei, B, Fiorelli, A, Leone, RJ, Chang, AS, Curcio, C, Sparks, P, Hagen, JA, Baste, JM, Taylor, L, Bilfinger, TV, Xavier, D, Engelhardt, K, Hall, DJ, Hansen, HJ, Leschber, G, Koryllos, A, Akopov, A, de Loos, ER, Karamustafaoglu, YA, Bertolaccini, L, Gandhi, S, Hendriks, JM, Batgirl, H, Hang Calvin, NS, Scanagatta, P, Prisciandaro, E, Gomez-Hernandez, MT, Sotiropoulos, G, Agrafiotis, AC, Furrer, M, Casiraghi, M, Cheufou, D, Mariani, AW, Novoa, N, Cassivi, SD, Veronesi, G, Gomez De Antonio, D, Bolca, C, Hamouri, S, Cattaneo, M, Stupnik, T
