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Silibinin exerts neuroprotective effects against cerebral hypoxia/reoxygenation injury by activating the GAS6/Axl pathway

N-acetyl lysyltyrosylcysteine amide inhibits myeloperoxidase, a novel tripeptide inhibitor

Bottom right: Clinical progression includes miosis, sweating, convulsions, respiratory paralysis, and potentially death within hours

Mori F, Barni S, Cianferoni A, Pucci N, De Martino M, Novembre E

Long-term efficacy and safety of pegcetacoplan over 36 months including 12-month results of the GALE open-label extension study

However, apocynin-mediated NOX inhibition is indirect, involving the presence of myeloperoxidase (MPO) together with H 2 O 2