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We then used the model to study different dosing strategies and found that modest differences result from different dosing strategies as long as they are started early enough (Figure12)

Briefly, cells (10,000/well) were seeded in 96-well plates

Treatment with -sitosterol ameliorates the effects of cerebral ischemia/reperfusion injury by suppressing cholesterol overload, endoplasmic reticulum stress, and apoptosis