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We also demonstrated that DPI significantly increases mitochondrial ROS production in MNA cells, but not in non-MNA cells, indicating a MYCN-dependent effect (16)

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J Biol Chem (2011) 286:517586

doi: 10.1111/nph.17612 31 HlskampM.MisaS.JrgensG

Despite the efficacy of conventional therapies, including antibiotics and retinoids, their use is frequently limited by adverse effects and the emergence of drug resistance