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2025;31(6):e70016

Mammals have 19 Wnt ligands and 10 FZD receptors, leading to a highly complex cascade of signaling responses (Nusse and Clevers, 2017

This interaction increases the risk of side effects like tremors, high blood pressure, and kidney toxicity

Interestingly, oxidatively modified biomolecules can not only be counteracted by direct repair or restoration responses but also serve as signaling molecules to participate in redox regulation