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This effect is likely to be mediated through several pathways: a) Upregulation of antioxidant enzymes: The significant increase in catalase levels observed in the IF group suggests that IF enhances endogenous antioxidant defenses, as catalase is a key enzyme in detoxifying hydrogen peroxide and mitigating oxidative stress

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Signaling in Caenorhabditis elegans development, metabolism, and aging

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12(S)-HETE promotes endocytosis of macrophages and promotes vascular inflammation

Published studies which reported differences in their observed phenotypes, utilised FRDA patient cells differing in the size of their repeat expansions to generate FRDA iPSCs and their derived models