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ALDH levels were measured in cultured neurons to test if disulfiram pharmaceutical formulations affect ALDH levels

This temporal correlation does not prove causation, but it supports the hypothesis that acetaminophen may be one of multiple environmental factors contributing to rising neurodevelopmental disorder rates, particularly in metabolically vulnerable populations unable to safely detoxify the drug

The safety database, while extensive for clinical trials, represents limited duration and population diversity compared to the variability encountered in clinical practice

Psychiatry 9, 522530

In terms of GI effects, it can cause gas, (sometimes with discharge), urgent or increased bowel movements, oily or fatty stools, loose stools, discolored stool, nausea, vomiting, diarrhea, and rectal and stomach pain