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KEGG pathway enrichment analysis showed that the DEGs were enriched in several immunologyrelated pathways (Figure 5D), such as Th17 cell differentiation [ko04659], Chemokine signaling pathway [ko04062], T cell receptor signaling pathway [ko04660], Th1 and Th2 cell differentiation [ko04658], Natural killer cell mediated cytotoxicity [ko04650], Leukocyte transendothelial migration [ko04670], B cell receptor signaling pathway [ko04662], Antigen processing and presentation [ko04612], NODlike receptor signaling pathway [ko04621], and Notch signaling pathway [ko04330]