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PMID: 11101503)

(1997).Increased nuclear ploidy, not cell proliferation, is sustained in the peroxisome proliferator-treated rat liver

The absence of evidence in this case is not an accident

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Real-world example: This distinction explains why someone who skipped a glass of water at dinner probably isnt experiencing a meaningfully different BAC than if theyd had that glass but someone who spent three hours in the sun at a summer festival without drinking any water, then started drinking alcohol, is in a genuinely different physiological state

National Research Council (2000)