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Like many emerging therapies, Dihexas clinical profile has its gaps: For this reason, Dihexa should always be used with functional lab support and under physician supervision

Unlike the PCSK9 trial, which targets a relatively rare gene variant associated with heart disease, these two trials are aimed at modifying the wild type, or common, version of a gene in individuals who may or may not have genetic risks for cardiovascular disease

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Humanized mice may therefore underestimate the relative importance of antibodies capable of neutralizing EBV infection of epithelial cells

In addition, other miRNAs, such as miR157 (He et al., 2014), miR319 (Fan et al., Figure 5C