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To identify the mechanisms underlying the cytotoxic effects of the NUPR1 inhibition in phBECs, we performed gene expression analysis of ferroptosis-related genes, lipid peroxidation assays, Annexin V/PI apoptosis/necrosis analysis and western blot analysis of ferroptosis and apoptosis-related genes

Neither peptide shows significant acute toxicity at standard doses based on available evidence

Effects vary depending on the type and severity of injury

Neuroscience 75:315323 Rust NC, LeDoux JE (2023) The tricky business of defining brain functions

Molecular Metabolism, 46, 101102

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