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the quality of your skin before treatment (stretch marks are a sure sign of very poor skin quality), and 2

GHK-Cu shifts expression of 4,000+ genes toward younger phenotypes upregulating DNA repair, collagen synthesis, and antioxidant pathways while suppressing inflammatory mediators

1998 Feb;25(2):155- 60

The REE was calculated using the O2 and CO2 levels, which were measured via indirect calorimetry for a duration of 30 minutes at controlled humidity and temperature