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Description

PD-1/PD-L1 inhibitor-associated liver injury exhibits significant histopathological heterogeneity, including varying degrees of lobular and/or portal inflammation, hepatocyte swelling with vacuolar degeneration, and focal necrosis

These were washed, passed through a 40m strainer and erythrocytes were lysed using ACK buffer (Thermo Fisher Scientific, Waltham, MA) following the manufacturers protocol

IGF-1 DES can alleviate inflammation IGF-1 DES can reduce inflammation and plaque in blood vessels, given the compounds ability to reduce endothelial cell oxidative stress