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Although increased GLR1 activity may be rationalized considering the increase of the GSSG substrate, the reason of the enhanced activity of GSH1 in CO23RFLC strain remains still unexplained (see Discussion)

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The development and progression of cancer from a premalignant lesion towards a metastatic tumor requires accumulation of mutations in many regulatory genes of the cell

SIRT1/Nrf2/NF-B signaling mediates anti-inflammatory and anti-apoptotic activities of oleanolic acid in a mouse model of acute hepatorenal damage