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10.1016/j.fertnstert.2014.02.002 44 RasmussenJ

The 25-mg twice-weekly dose has been largely replaced by the 50-mg prefilled syringe and auto-injectors, which are equally effective

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While such a blood type mismatch is not uncommon, it can result in alloimmunization when combined with fetal-maternal bleeding, which occurs in around 5% of pregnancies and increases throughout the gestation period [172]

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It was designed to specifically target the autoimmune response against double-stranded DNA, one of the hallmark autoantibody targets in lupus