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Mol Cell Endocrinol 5(455):115130 Zhou J, Zhou F, Wang W, Zhang XJ, Ji YX, Zhang P, She ZG, Zhu L, Cai J, Li H (2020) Epidemiological features of NAFLD from 1999 to 2018 in China

The pattern is consistent: researchers who follow a structured titration protocol with pre-specified timing windows report cleaner data and fewer early discontinuations due to adverse events