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Melasma can return if triggers such as sun exposure or hormones persist

These studies have investigated the use of exosomes as effective brain-targeted drug delivery systems to increase drug efficacy and reduce side effects

Conventional solvent extraction remains widely used, but newer technologies offer significant advantages in terms of yield and quality

defined as partial Mayo score 2 without steroids) at week 12, endoscopic remission (CFREM + endoscopic Mayo score 1) at week 12, time to first biologic discontinuation, time to first hospitalization and time to colectomy

(Reference Kuriyama, Hozawa, Ohmori, Shimazu, Matsui and Ebihara4Reference Unno and Nakamura6) The chemical structure of catechins generally determines their potential bioactivities