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Although the results for tHcy in younger populations are confirmed, the negative associations between elevated plasma vitamin B12 concentrations and mortality in this situation are novel and need more research [78]

This is the most consistently reported side effect and tends to persist

This bypasses the digestive system, where B12 from food or supplements can be poorly absorbedespecially in individuals with gastrointestinal conditions, certain medications, or restrictive diets

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While each compound serves a different role, combined studies often produce stronger data sets