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Mechanistically, ROS maintains ERK signaling activity by inhibiting ERK phosphatase dualspecific phosphatase 3 (DUSP3) resulting in increased cell migration and EMT [53, 90]

Wang R., Zhao J., Zhang J., et al., Effect of Lysosomal and Ubiquitinproteasome System Dysfunction on the Abnormal Aggregation of synuclein in PC12 Cells, Exp Ther Med 9, no