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The use of such an ROS-responsive nanoplatform for drug formulation modification may provide a new strategy for not only the delivery of deucravacitinib but also other small-molecule drugs in the JAK family, which can offer a promising clinical translation strategy

Cell 113 , 673676 (2003)

Therefore, neutrophils are a major contributor to the development of ALD, and targeting them may be a promising therapeutic strategy for ALD

Ki-67 immunostaining was performed for tumor specimens in various groups according to the standard protocol

doi: 10.1136/annrheumdis-2019-215763 20 WangWYangGJZhangJChenCJiaZYLiJet al

Previous studies have reported that PKM2 is enzymatically active toward pyruvate only as a tetramer and acts as a transcription factor coactivator when tetrameric PKM2 dissociates into a dimer 28,29