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Description

It should be noted that glutamate derived from glutamine may also undergo transamination reactions (Figure 3), which could lead to overestimations of glutamine oxidation when only assessing metabolic connections between amino acids

Redox compartmentalization and cellular stress

Inhibitors of Dimerization HIF-1 dimerization has been reported to be disrupted and its transcriptional activity inhibited by cyclic peptide inhibitor (cyclo-CLLFVY), which binds to the HIF-1 PAS-B region (Figure 5)