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This indicated that GSNOR was not involved in H 2 O 2 consumption through a non-enzymic system

Electrophilic properties of itaconate and derivatives regulate the IB-ATF3 inflammatory axis

Reactive oxygen species (ROS) are mediator of cellular injury and play an important role in hepatic damage during GalN-induced hepatitis

Diclofenac sodium, a non-steroidal anti-inflammatory drug (NSAID), is effective in reducing inflammation, pain, and swelling, providing a dual-action formulation that addresses both the symptoms and underlying causes of pain

In contrast, LDH-B transform lactate into pyruvate, allowing cells to use lactate as a source of nutrients for oxidative metabolism ( ( Figure 1 ) ( An increase of LDH-A expression is key in the metabolism of cancer cells and is considered a negative prognostic biomarker ( D-lactate is derived from carbohydrate metabolism and lipids through the formation of methylglyoxal (MG) ( ( Figure 2 )

In this study, all methods were carried out in accordance with applicable guidelines, rules, and regulations and was started after the approval of the Shahid Beheshti University of Medical Sciences ethics committee and after obtaining the code of ethics (IR.SBMU.MSP.REC.14001555)