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The key is to treat optimization like an experiment measure, adjust, and let your physiology guide the protocol changes (if any)

(2019) 177:126279.e25

It is the primary cause of mortality among different cancer types, as well as breast cancer (115)

Animals were tested every other day

Immunofluorescence images were acquired using an inverse point scanning confocal Zeiss LSM980 Microscope equipped with a Zeiss Plan-Apochromat 63x/1.4 Oil DIC M27 (WD 0.19 mm) running with Zeiss ZEN Blue 3.3 software (version 3.3.89.0008)