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Mutations in the SLC3A1 transporter gene in cystinuria

To explain this finding, it may be noted that GltT, although required for L-glutamate transport, is highly homologous to the VacJ/Yrb ABC transport system, a proposed phospholipid transporter for maintaining lipid asymmetry in the Gram-negative outer membrane (Mla pathway) (Malinverni and Silhavy, 2009), also involved in outer membrane vesicle (OMV) formation (Roier et al., 2016)

By delivering GHK-Cu beneath the surface, these treatments aim to support regeneration from the inside out, complementing and sometimes amplifying the effects of traditional topical products

Gastroenterology 152 , 14621476.e10 (2017)

22, S15S22

In contrast, menadione, an inducer of oxidative stress, increased GPX3 expression in phLF, but not in phBEC (Figs 7C and 8C, respectively)