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Acknowledgements The authors acknowledge financial support from the Natural Science Foundation of China (NSFC No

Tertiary structure model was based on template c1gpmD, which followed the PDB title, Escherichia coli GMP synthetase complexed with amp and pyrophosphate

This can be especially beneficial during cold and flu season, or for individuals who are recovering from illness and need a boost to their immune defenses

Different pathological glial phenotypes may co-exist in the same pathological process or can be associated with different stages of the disease or disorder

Three human serum samples were assayed in replicates of 20 to determine precision within an assay (CV = Coefficient of Variation)

Subsequently the detached leaves were placed in dark with high humidity for 23 days