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Researchers say quitters who gain a few pounds still have about a 50% lower risk of heart disease than smokers

For many guys, quitting cold turkey is unsuccessful, says Bill Blatt, M.P.H., the director of Tobacco Programs for the American Lung Association

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Similarly, ROS induced in the lung as a result of tobacco smoke exposure also activate the NFE2-like bZIP transcription factor 2 (NRF2) pathway (63), which has been shown to upregulate the PPP (64), potentially linking tobacco smoke exposure to inflammation-associated metabolic reprogramming that may contribute to CR production

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