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High-dose folic acid supplementation results in significant accumulation of unmetabolized homocysteine, leading to severe oxidative stress in Caenorhabditis elegans

However, in July 2018, it was reported that an error had occurred in 2016 in which two lots of the same medicines were dispensed and supplied to the same patient, Richard Lee, who subsequently died

Alpha lipoic acid acts synergistically with berberine in this energy-restoring process

Reactive astrocytosis is a consistent pathological hallmark not only in AD, but also in PD, ischemic stroke, and ALS

This review article aims to explore and summarise the correlation between potential mitochondrial dysfunction caused by selected pharmacological agents and its effect on insulin signalling and glucose handling

A deeper understanding of the potential interaction between genetic and environmental factors would be instrumental to deepen this debate, and for the development of preventive strategies for patients and their family members