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Description

421,459,460 The thalamus plays a pivotal role in modulating and processing somatosensory inputs before they reach the cerebral cortex and may serve as a central biomarker for neuropathic pain in diabetes mellitus

The primary endpoint in these rigorous trials is typically the Total Symptom Score (TSS), which quantitatively evaluates the severity of burning, pain, tingling, and numbness in the extremities